Endocrine Abstracts

Background: Previous cross-sectional studies have described amenorrhea in cohorts of transgender men on intramuscular or subcutaneous testosterone injections. It remains uncertain which testosterone preparations most effectively suppress vaginal bleeding and when amenorrhea occurs after testosterone initiation.Aim: To investigate the clinical effects of various testosterone preparations on vaginal bleeding and spotting in transgender men.<p class="ab...

Introduction: If desired, options for gender affirming treatment in transgender individuals may involve gender affirming hormonal therapy. However, the effects on fertility and testicular function are less known. Several studies have been performed with variable results regarding germ cell maturation and testicular function in this population. In order to give correct information to all transgender women, we find it important as a referral center for transgender care, to compa...

Aim: The changes in serum oestradiol levels in assigned female at birth (AFAB) transgender people receiving testosterone therapy have not been elucidated. How serum oestradiol levels change after initiation of testosterone therapy, if these levels should be monitored and whether altered oestradiol levels will result in adverse health outcomes, remains unclear.Methods: This prospective cohort study was part of the European Network for the Investigation of...